A Phylogenetic Approach to Inferring the Order in Which Mutations Arise during Cancer Progression
Y. Gao, J. Gaither, J. Chifman, L. Kubatko
This paper introduces a method to infer the order of somatic mutations in cancer progression using noisy single-cell sequencing data and demonstrates its effectiveness through simulations and empirical data.
bioRxiv · May 6, 2020Cancer Biology