Author

J. M. Siegfried

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Almotlak· 1 shared C. R. Wagner· 1 shared M. R. Matos de Souza· 1 shared O. Kilic· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBioengineering

A. A. Almotlak

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1 paper

Recent·Most cited

BioengineeringbioRxivApr 22, 2020

Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression

O. Kilic, M. R. Matos de Souza, A. A. Almotlak…·C. R. Wagner

This paper demonstrates that EGFR-targeting fibronectin-based PARs suppress tumor growth in vivo by modulating the tumor microenvironment and reducing PD-1/PD-L1 expression.

DOI 10.1021/acs.jmedchem.0c00489

mouseproteomics