Inflammation is the main risk factor of voriconazole overdose in hematological patients
E. Gautier-Veyret, A. Truffot, S. Bailly, X. Fonrose, A. Thiebaut-Bertrand, J. Tonini, J.-Y. Cahn, F. Stanke-Labesque
The paper identifies inflammation, measured by CRP levels, as the main risk factor for voriconazole overdose in hematological patients, while pharmacogenetic factors are not significant.
bioRxiv · May 21, 2018Pharmacology & Toxicology