Protein products of non-stop mRNA disrupt nucleolar homeostasis
Z. H. Davis, L. Mediani, J. Vinet, S. Alberti, A. S. Holehouse, S. Carra, O. Brandman
This study shows that nonstop mRNA proteins accumulate in nucleoli, disrupting their structure and function, and links this to neurodegeneration mechanisms.
bioRxiv · Nov 22, 2019 · PreprintCell Biology