Elastin-derived peptides favor type 2 innate lymphoid cells in COPD
S. Lahire, C. Fichel, O. Rubaszewski, C. Lereverend, S. Audonnet, V. Visneux, J.-M. Perotin, G. Deslee, S. Le Jan, S. Potteaux, R. Le Naour, A. Pommier
This study shows that elastin peptides in COPD patients increase ILC2 activation through IL-5 secretion by macrophages, highlighting a potential therapeutic target.
bioRxiv · Sep 13, 2023Immunology