Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue
Jack Stein, D’Artagnan Greene, Flavio H. Fenton, Yohannes Shiferaw
This study develops a computational model of early after depolarizations (EADs) in cardiac tissue, showing that EADs can emerge through a discontinuous bifurcation leading to arrhythmogenic alternans without ectopic beats.
PLoS Computational Biology · Apr 22, 2025Peer-reviewedSynthetic Biology