Cell BiologybioRxivPreprint
Targeted Protein Degradation of NUDT5 Reveals an Unexpected Non-Enzymatic Role in 6-Thioguanine-Mediated Toxicity
Anne-Sophie M. C. Marques, Ludwig G. Bauer, Tuan Anh Nguyen…·K. Huber
The paper develops NUDT5 degraders and shows NUDT5 has a non-enzymatic role in 6-TG toxicity, distinct from NUDT15.
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