AAV-Mediated Ribozyme Targeting of HSV-1 Latency-Associated Transcript RNAs Reveals Distinct Functions of the LAT Intron and Exon In Vivo
Mason A. Shipley, Jasbir Singh, David C. Bloom, Donna M. Neumann
This study uses ribozymes to target HSV-1 LAT RNA components in vivo, revealing distinct roles of the LAT intron and exon in latency and reactivation.
bioRxiv · Oct 14, 2026 · PreprintMicrobiology