Notch-signaling is required for mediating between two pattern forming processes during head regeneration in Hydra polyps
Mona Steichele, Lara Sauermann, Qin Pan, Jasmin Moneer, Alexandra de la Porte, Martin Heß, Moritz Mercker, Catharina Strube, Heinrich Flaswinkel, Marcell Jenewein, Angelika Böttger
The paper shows Notch signaling inhibits tentacle production during Hydra head regeneration, allowing hypostome/organizer formation, and identifies HyKayak as a Notch target gene.
bioRxiv · Feb 2, 2024 · PreprintDevelopmental Biology