Imaging CRISPR-Edited CAR-T Cell Therapies with Optical and Positron Emission Tomography Reporters
Rafael E. Sanchez‐Pupo, John Joseph Kelly, Nourhan Shalaby, Ying Xia, Francisco Martínez‐Santiesteban, Jasmine Lau, Ivy E. Verriet, Matthew S. Fox, Justin W. Hicks, Jonathan Dale Thiessen, John Andrew Ronald
This paper develops tRACE-CAR T cells with optical and PET imaging reporters to track CAR-T cell distribution and activity in vivo, showing improved tracking and therapeutic effectiveness.
Theranostics · Jan 1, 2026Peer-reviewedImmunology