Contrastive Regulatory Embeddings Attention Model for Differential Expression Prediction with Personalized Genomes: Insights and Challenges
Zhirui Hu, Jason Ku, Katherine S. Pollard
This paper introduces CREAM, a deep learning model for differential expression prediction using personalized genomes, showing improved performance on training genes but challenges in generalizing to unseen genes.
bioRxiv · Aug 5, 2026 · PreprintBioinformatics