Coalescent inference using serially sampled, high-throughput sequencing data from intra-host HIV infection
Kevin Dialdestoro, Jonas Andreas Sibbesen, Lasse Maretty, Jayna Raghwani, Astrid Gall, Paul Kellam, Oliver Pybus, Jotun Hein, Paul Jenkins
This paper introduces a method to infer evolutionary dynamics of intra-host HIV using deep sequencing data, finding mutation rates and population sizes comparable to BEAST.
Genetics · Feb 5, 2016Peer-reviewedGenetics