Jerry Antone

A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease

The paper provides a public resource of single nucleus RNA sequencing data and multiscale networks from Alzheimer's disease and non-disease individuals, linking genetic variants to molecular features and revealing novel disease biology.

Cryopreservation of cerebrospinal fluid cells preserves transcriptomics integrity for single-cell analysis

This study shows that cryopreservation of CSF cells using FBS/DMSO or Recovery media preserves transcriptomic integrity for single-cell analysis, enabling accurate cell type detection and gene expression profiling.

The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

The paper presents a multi-layered molecular dataset from iPSC-derived dopaminergic neurons to model Parkinson's disease genetic risk and provides a data browser for accessing these resources.

Modelling dementia in Drosophila uncovers shared and specific targets of TDP-43 proteinopathy across ALS and FTD relevant circuits

This study uses a Drosophila model to investigate TDP-43 proteinopathy in ALS and FTD, identifying shared and circuit-specific molecular targets.

Dynamic Transcriptomic Network Responses to Divergent Acute Exercise Challenges in Young Adults

The paper compares transcriptomic responses in skeletal muscle and extracellular vesicles after traditional and high-intensity exercise in young adults, finding more consistent gene responses to traditional exercise and unique microRNA responses to high-intensity training.