Author

Jessica Lagerwall

Lund University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Austin KangiD· 1 shared Bob A. HersbachiD· 1 shared C. Frank BennettiD· 1 shared Carlota Tosat‐BitriániD· 1 shared Daniela A. GrassiiD· 1 shared Dylan A. ReidiD· 1 shared Emma E Taylor· 1 shared Fred H. GageiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Austin KangORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cytoplasmic DNA Sensing Links LINE-1 Expression to Neuronal Senescence in Alzheimer's Disease

Joseph R. Herdy, Emma E Taylor, Lukas Karbacher, Oliver Borgogno, Larissa Traxler, Jessica Lagerwall, Vincent A. Huynh, Zornitsa V Lefterova, Austin Kang, Carlota Tosat‐Bitrián, Maxfield M. G. Kelsey, John M. Sedivy, Subhash C. Sinha, Li Gan, C. Frank Bennett, , Fred H. Gage

This study identifies LINE-1 retrotransposons as drivers of neuronal senescence in Alzheimer's disease through cytoplasmic DNA sensing and the cGAS-STING pathway.

bioRxiv · Jul 28, 2026 · PreprintNeuroscience

Distinct sub-cellular autophagy impairments occur independently of protein aggregation in induced neurons from patients with Huntington's disease

Karolina Pircs, Janelle Drouin‐Ouellet, Jeovanis Gil, Melinda Rezeli, Daniela A. Grassi, Raquel Garza, Yogita Sharma, Isabelle St‐Amour, Marie E. Jönsson, Pia Annette Johansson, Kate L. Harris, Romina Vuono, Thomas B. Stoker, Bob A. Hersbach, Kritika Sharma, , Johan Jakobsson

This study shows that induced neurons from Huntington's disease patients have impaired autophagy in neurites, independent of protein aggregation, and that HTT is critical for neuronal autophagy.

bioRxiv · Mar 1, 2021 · PreprintNeuroscience