Author

Jiale He

Frontiers Science Center for Synthetic Biology, Key Laboratory of Systems Bioengineering (MOE), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, ChinaPrimary ORCID profile (0009-0002-6240-0256 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Jiale HeiD1 paper · Shandong University

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Approach:experimental assay· 1

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Fan CheniD· 1 shared Min DongiD· 1 shared Yadi Yao· 1 shared

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BiochemistrybioRxivFeb 1, 2024

Arsinothricin Biosynthesis Involving a Noncanonical Radical SAM Enzyme for C-As Bond Formation

Yadi Yao, Jiale He, Fan Chen, Min Dong

This paper characterizes ArsL, a noncanonical radical SAM enzyme involved in arsinothricin biosynthesis, showing it cleaves SAM to generate an ACP radical and reconstitutes the pathway in vitro.

DOI 10.1021/jacs.4c06403

experimental assay