Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation
Xiangru Huo, Denis L. Lafontaine, Thomas M. Reimonn, Liyan Yang, Richard Siller, Jack D. Huey, Jiang Min, Aleksandra A. Galitsyna, Vedat Yilma, Krishna Mohan Parsi, Emily Navarrete, Hoang Tran, Leonid A. Mirny, René Maehr, Johan Harmen Gibcus, , Nezar A. Abdennur
The paper temporally maps nuclear reorganization during human stem cell differentiation and identifies three temporally ordered transitions in nuclear structure and function.
bioRxiv · Sep 18, 2026 · PreprintGenomics