Jitendriya Swain

SARS-CoV-2 nucleocapsid protein engages with viral RNA and ERGIC lipids to drive viral core assembly

This study shows that SARS-CoV-2 nucleocapsid protein interacts with viral RNA and ERGIC lipids to drive viral core assembly through lipid clustering and RNP stabilization.

Human pluripotent stem cell-derived bronchial airway organoids provide insights into differential innate immune and long-term responses to SARS-CoV-2 infection in healthy and COPD.

This study uses human iPSC-derived bronchial organoids to show SARS-CoV-2 causes prolonged infection, cilia destruction, and differential innate immune responses in healthy and COPD models.

The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery

This study identifies the Coxiella effector Vice as a protein that manipulates host cell lipid composition and cellular pathways to form the Coxiella-containing vacuole.