The Plateau Method for Forensic DNA SNP Mixture Deconvolution
Darrell O. Ricke, Joe Isaacson, James Watkins, Philip Fremont‐Smith, Tara Boettcher, Martha S. Petrovick, Edward C. Wack, Eric D. Schwoebel
The paper introduces the Plateau method to deconvolve DNA mixtures into individual sub-profiles using SNP data without reference profiles, detecting contributors as low as 1/200 in concentration.
bioRxiv · Nov 27, 2017 · PreprintBioinformatics