SignalGen: A Protein Language Model Based AI Agent For Optimal Signal Peptide Prediction
Joe McKenzie, Hung Nguyen Do, Apoorv Shanker, Jessica Z. Kubicek-Sutherland, Sandrasegaram Gnanakaran
SignalGen predicts optimal signal peptides for protein expression by integrating mature protein sequences, organism, and localization using a Latent Residual Transformer.
bioRxiv · Nov 12, 2025 · PreprintBioinformatics