Single-cell mapping of regulatory DNA:Protein interactions
Wei-Yu Chi, Sang-Ho Yoon, Evrim Goksel, Levan Mekerishvili, Joe Pelt, Yiyun Lin, Tamara Prieto, John Zinno, Saravanan Ganesan, Catherine J. Potenski, Franco Izzo, Dan Avi Landau, Ivan Raimondi
This paper introduces D&D-seq, a single-cell method to map DNA:Protein interactions with high specificity and resolution, and applies it to study TF binding in human cells.
Cell · Jun 1, 2026Peer-reviewedGenomics