Plasma Cell-Free DNA in Acute and Chronic Aortic Syndromes.
Ruwan Alwis Weerakkody, Martyna Joanna Adamowicz, Christelle Robert, John D. Pound, Maaz B. J. Syed, Caroline Pumpe, Anwar Muhammad Bilal, Alexander Laird, Duncan B. McLaren, Orwa Falah, Andrew L. Tambyraja, Matthew James Reed, David Ernest Newby, Timothy J. Aitman
The paper shows plasma short-fragment cfDNA concentration is higher in acute and chronic aortic disease compared to controls and is higher in acute cases, suggesting it could be a diagnostic biomarker.
bioRxiv · Jan 6, 2025 · PreprintGenomics