Author

John Harding

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ancy JosephiD· 2 shared Daniel A. RauchiD· 2 shared Lee RatneriD· 2 shared Malachi GriffithiD· 2 shared Anam Fahad· 1 shared Deborah V. NovackiD· 1 shared Isabel RischiD· 1 shared Jacob Al-SaleemiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Ancy JosephORCID

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Author profile →

2 papers

Recent·Most cited

Role of the CTCF Binding Site in Human T-Cell Leukemia Virus-1 Pathogenesis

Ancy Joseph, Xiaogang Cheng, John Harding, Jacob Al-Saleem, Patrick A. Green, Malachi Griffith, Deborah V. Novack, Daniel A. Rauch, Lee Ratner

This study shows that the CTCF binding site in HTLV-1 regulates viral pathogenesis by affecting proviral load, Tax expression, and T-cell activation in humanized mice.

PLoS Pathogens · Jun 3, 2025Peer-reviewedMicrobiology

Single-Cell Transcriptomic Analysis of Kaposi Sarcoma

Daniel A. Rauch, Paula Valiño Ramos, Mariam Khanfar, John Harding, Ancy Joseph, Anam Fahad, Paul D. Simonson, Isabel Risch, Obi L. Griffith, Malachi Griffith, Lee Ratner

This study uses single-cell RNA sequencing to analyze Kaposi Sarcoma tumors and blood samples, identifying KSHV-infected cell types and their biomarkers, and showing changes with therapy.

PLoS Pathogens · Apr 1, 2025Peer-reviewedCancer Biology