Author

Joseph Beechem

Primary ORCID profile (0000-0001-8372-5899 · 20 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Joseph BeechemiD20 papers · Nanostring Technologies (United States)

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Lucas Dennis· 2 shared Patrick Danaher· 2 shared Alice Wang· 1 shared Andrew McDavidiD· 1 shared Andrew White· 1 shared Greg FinakiD· 1 shared Kunle Odunsi· 1 shared Leonard D'Amico· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Lucas Dennis

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2 papers

Recent·Most cited

Gene expression markers of Tumor Infiltrating Leukocytes

Patrick Danaher, Sarah Warren, Lucas Dennis, Leonard D'Amico, Andrew White, Mary L Disis, Melissa A Geller, Kunle Odunsi, Joseph Beechem, Stephen P Fling

The paper identifies 60 gene markers for 14 immune cell types in tumors, validated through co-expression analysis in TCGA data and compared to flow cytometry and IHC.

bioRxiv · Aug 11, 2016Bioinformatics

Modeling bi-modality improves characterization of cell cycle on gene expression in single cells

Lucas Dennis, Andrew McDavid, Patrick Danaher, Greg Finak, Michael Krouse, Alice Wang, Philippa Webster, Joseph Beechem, Raphael Gottardo

The paper models bi-modality in single-cell gene expression to improve characterization of cell cycle effects and finds the cell cycle explains 5%-17% of expression variability.

PLoS Computational Biology · Jul 17, 2014Peer-reviewedBioinformatics