Stage-Specific NF-κB RelA and IRF4 Programs Drive -Synuclein-Induced Disease-Associated Microglia Differentiation
Yating Yang, Yves Greatti, Aidan T. Miller, Jhodi M. Webster, Asta Jurkuvenaite, Josh Randolph, Osama Al‐Dalahmah, David A. Figge, Ashley S. Harms
This study identifies NF-κB RelA and IRF4 as stage-specific regulators driving -synuclein-induced disease-associated microglia differentiation in Parkinson disease.
bioRxiv · Sep 30, 2026 · PreprintImmunology