Developmental BiologyJournal of Bone and Mineral ResearchPeer-reviewed
Osteocyte death and bone overgrowth in mice lacking Fibroblast Growth Factor Receptors 1 and 2 in mature osteoblasts and osteocytes
Jennifer A. McKenzie, Craig R. Smith, Kannan Karuppaiah…·David M. Ornitz
This study shows that loss of FGFR1 and FGFR2 in mature osteoblasts/osteocytes leads to osteocyte death and high bone mass with impaired biomechanical properties in mice.
39 citations