Epigenetic signature of human immune aging: the GESTALT study.
Roshni Roy, Pei‐Lun Kuo, Julián Candia, Dimitra Sarantopoulou, Ceereena Ubaida‐Mohien, Dena G. Hernandez, Mary Kaileh, Sampath Arepalli, Amit Singh, Arsun Bektas, Jae‐Kwan Kim, Ann Zenobia Moore, Toshiko Tanaka, Julia McKelvey, Linda M. Zukley, , Luigi Ferrucci
The paper identifies age-associated DNA methylation sites in immune cells and links them to transcription factor motifs and histone modifications, suggesting adaptive responses to oxygen fluctuations in aging.
eLife · Aug 17, 2023Peer-reviewedMolecular Biology