ImmunologybioRxiv
T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells
Josep Garnica, Patricia Solé, Jun Yamanouchi…·Pere Santamaría
The paper investigates the epigenetic mechanisms enabling T-follicular helper cells to transdifferentiate into TR1 cells, finding that TR1 gene programs are pre-established in TFH cells.
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