Alpha-1-antitrypsin (AAT) inhibits Mycobacterium intracellulareinduction of monocyte colony stimulating factor: another host defense function of AAT
Xiyuan Bai, Drew E. Narum, Carla Eyre, Junfeng Gao, Edward D. Chan
This study shows AAT inhibits MAC-induced M-CSF but not GM-CSF in macrophages, suggesting a role in modulating host defense against mycobacteria.
bioRxiv · Feb 21, 2026 · PreprintImmunology