Skin-derived G-CSF activates pathological granulopoiesis upon psoriasis
Tomson Kosasih, Tatsuya Morishima, Sohyeon Lee, Jungyeon Yoon, Kanako Wakahashi, Pilhan Kim, Aiko Sada, Hitoshi Takizawa
The paper identifies G-CSF produced by skin endothelial cells as a driver of pathological granulopoiesis and neutrophil infiltration in psoriasis, offering a potential therapeutic target.
EMBO Molecular Medicine · Jun 16, 2026Peer-reviewedImmunology