Metacontam: A Negative Control-Free Decontamination Method for Metagenomic Analysis
Junwoo Jo, Hyeyoung Lee, Jae Woo Baek, Suyeon Lee, Vikas Singh, Adil Mardinoğlu, Saeed Shoaie, Jinwook choi, Sunjae Lee
Metacontam is a decontamination method for metagenomic data that improves detection of low-abundance contaminants without needing negative controls.
bioRxiv · Apr 29, 2026 · PreprintBioinformatics