Class A PBPs reinforce the septal cell wall following initial synthesis by SEDS-bPBP pairs during bacterial cytokinesis
Jiajia Wang, Jie Hu, Yue Xin, Lihao Ding, Xinci Wang, Xianglong Ou, Junyi Pang, Yongfeng Liu, Sijing Zhang, Liang Zhang, Hui Wang, Chun-ying Yin, Yongxiang Gao, Ting Xue, Yandong Yin, , Xinxing Yang
The paper shows that SEDS-bPBP pairs initiate septal PG synthesis during bacterial cytokinesis, while class A PBPs reinforce the septal wall later in the process.
bioRxiv · Sep 12, 2025 · PreprintMicrobiology