Antiretroviral APOBEC3 Cytidine Deaminases Alter HIV-1 Provirus Integration Site Profiles
H. O. Ajoge, T. M. Renner, K. Belanger, H. P. Kohio, M. D. Coleman, M.-A. Langlois, S. D. Barr
This study shows APOBEC3 proteins alter HIV-1 integration site preferences by reducing insertions into genes and increasing them into SINE elements and non-B DNA regions.
Nature Communications · Jan 10, 2023Peer-reviewedMicrobiology