Alterations in Lipid Saturation Trigger Remodeling of the Outer Mitochondrial Membrane
Sara Wong, K. Bertram, Sai Sangeetha Balasubramaniam, Nidhi Raghuram, Thomas J. Knight, J. Alan Maschek, James Eric Cox, Adam L. Hughes
This study shows that increased unsaturated fatty acids remodel the mitochondrial outer membrane by promoting the formation of mitochondrial-derived compartments and impairing TOM complex assembly.
Molecular Biology of the Cell · Jul 30, 2025Peer-reviewedCell Biology