Cancer BiologybioRxiv
Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+ T cells in the tumor microenvironment and predicts clinical outcome in early- and late-phase clinical trials
A. Roller, I. I. Davydov, P. C. Schwalie…·M. A. Cannarile
This study develops a transcriptome-based classifier to predict CD8+ T cell spatial infiltration patterns in the tumor microenvironment and shows its prognostic and predictive value across clinical trials.
DOI 10.1136/jitc-2023-008185