PCK2 opposes mitochondrial respiration and maintains the redox balance in starved lung cancer cells
K. Leithner, G. Grasmann, M. Planque, C. T. Madreiter-Sokolowski, A. Hrzenjak, W. F. Graier, S.-M. Fendt, H. Olschewski
This study shows PCK2 regulates mitochondrial respiration and redox balance in starved lung cancer cells by modulating TCA cycle intermediates and glutathione oxidation.
bioRxiv · Nov 23, 2020Cancer Biology