Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
K. Todkar, L. Chikhi, V. Desjardins, F. El-Mortada, G. Pepin, M. Germain
The paper shows cells selectively package mitochondrial proteins into EVs while excluding damaged proteins, using distinct MDVs pathways and Parkin to prevent inflammation.
bioRxiv · Mar 13, 2020Cell Biology