Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics
N. C. Gassen, J. Papies, T. Bajaj, F. Dethloff, J. Emanuel, K. Weckmann, D. E. Heinz, N. Heinemann, M. Lennarz, A. Richter, D. Niemeyer, V. M. Corman, P. Giavalisco, C. Drosten, M. A. Muller
This study identifies spermidine, MK-2206, and niclosamide as potential antiviral therapeutics by enhancing autophagy against SARS-CoV-2 in vitro.
bioRxiv · Apr 15, 2020Microbiology