Author

Kai Cai

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert HungiD· 1 shared Brian CoventryiD· 1 shared Catherine HalliD· 1 shared David A. BakeriD· 1 shared David S. LeeiD· 1 shared Domenico AcciliiD· 1 shared Eunhee ChoiiD· 1 shared Jie LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Albert HungORCID

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1 paper

Recent·Most cited

BioengineeringMolecular CellPeer-reviewedOct 15, 2025

Tuning Insulin Receptor Signaling Using De Novo Designed Agonists

Xinru Wang, Sarah Caixeta Cardoso, Kai Cai…·David A. Baker

This paper designs synthetic insulin receptor agonists that modulate receptor conformation and signaling, showing improved potency and activity in disease mutants.

25 citationstop 2%

humanproteomics