Author

Kai ye

MOE Key Lab for Intelligent Networks & Networks Security, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China; School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Ji;

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Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:imputation· 1 Assay:long-read sequencing· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdel Abdellaoui· 1 shared Alexander Schöenhuth· 1 shared André G. Uitterlinden· 1 shared Bradley P. Coe· 1 shared Chuyuan Lou· 1 shared Cisca Wijmenga· 1 shared Dan Xu· 1 shared Deyu MengiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Abdel Abdellaoui

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2 papers

Recent·Most cited

Cellular context shapes the transcriptomic impact of somatic variants

Peisen Sun, Peng Jia, Chuyuan Lou, Xiaona Li, Miaojing Li, Ruifen Zhang, Hui Lin, Xiujuan Li, Yunsong Zhou, Shuzheng Cai, Zexin Zhang, Pengyu Zhang, Tun Xu, Songbo Wang, Yudong Wang, , Kai Ye

The paper shows that somatic variants' transcriptomic impact depends on cellular context, not just sequence, using single-cell transcriptomics and new tools.

bioRxiv · Nov 2, 2026 · PreprintGenetics

A high-quality reference panel reveals the complexity and distribution of structural genome changes in a human population

Jayne Y. Hehir-Kwa, Tobias Marschall, Wigard P. Kloosterman, Laurent C. Francioli, Jasmijn A. Baaijens, Louis J. Dijkstra, Abdel Abdellaoui, Vyacheslav Koval, Djie Tjwan Thung, René Wardenaar, Ivo Renkens, Bradley P. Coe, Patrick Deelen, Joep de Ligt, Eric-Wubbo Lameijer, , Victor Guryev

This study creates a high-quality reference panel of structural variants from 769 Dutch individuals, revealing new variants and their linkage to known SNPs, improving imputation accuracy for genome-wide association studies.

bioRxiv · Jul 2, 2016 · PreprintGenetics