Protein-level mapping reveals novel Immune State Types (ISTs) associated with Chlamydia trachomatis infection, inflammatory remodeling, and scarring in trachoma-hyperendemic Amhara Ethiopia
Xiaoyi Charlotte Shi, Olusola Olagoke, Brianna Renatte Titiheruw, Seongwon Chung, Hiwot Degineh Mengistie, Kaleb Asfaha, Timothy D. Read, Deborah Dean
The paper identifies four immune state types (ISTs) in trachoma patients using protein profiling, linking them to infection, inflammation, and scarring outcomes.
bioRxiv · Oct 6, 2026 · PreprintMicrobiology