Author

Kara Han

Centre for Addiction and Mental Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Bhooma ThiruvahindrapuramiD· 2 shared Brett TrostiD· 2 shared Giovanna PellecchiaiD· 2 shared Marla Mendes de AquinoiD· 2 shared Rayssa M.M.W. FeitosaiD· 2 shared Worrawat EngchuaniD· 2 shared Xiaopu ZhouiD· 2 shared Adam X. MaihoferiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Bhooma ThiruvahindrapuramORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evaluating the impact of compound heterozygosity involving microdeletions and sequence-level variants: findings in autism

Worrawat Engchuan, Kara Han, Rayssa M.M.W. Feitosa, Nelson Bautista Salazar, David J. Mager, Shania Wu, Faraz Ali, Alex W.H. Chan, Marla Mendes de Aquino, Xiaopu Zhou, Rulan Shaath, Nickie Safarian, Bhooma Thiruvahindrapuram, Thomas Nalpathamkalam, Giovanna Pellecchia, , Jacob A. S. Vorstman

The paper evaluates the role of compound heterozygous deletion events in autism by analyzing 9,766 families and finds modest enrichment of rare DelCH events in autistic individuals.

medRxiv · Oct 17, 2025 · PreprintGenetic & Genomic Medicine

Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects

Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R. MacDonald, Bhooma Thiruvahindrapuram, Omar Hamdan, Marieke Klein, Adam X. Maihofer, James Guevara, Oanh Hong, Guillaume Huguet, Molly Sacks, Mohammad Mehdi Ahangari, Rayssa M.M.W. Feitosa, Kara Han, , Michael Foster Green

The paper identifies shared and divergent genetic mechanisms across psychiatric disorders using gene-set burden analysis of copy number variants.

medRxiv · Jul 11, 2025 · PreprintGenetic & Genomic Medicine

BrainRBPedia: a resource for RNA-binding proteins relevant to neurodevelopmental disorders

Kara Han, Michael Wainberg, John A. Calarco, Craig A. Smibert, Howard D. Lipshitz, Hyun O. Lee, Shreejoy J. Tripathy

BrainRBPedia is a database of 1072 RNA-binding proteins linked to neurodevelopmental disorders, with a machine learning model prioritizing RBPs for autism and intellectual disability.

bioRxiv · Jun 7, 2023 · PreprintBioinformatics