Author

Kate Louderback

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adele Bubnys· 1 shared Alan Y. L. JiangiD· 1 shared Anna BrightiD· 1 shared Carles A. BoixiD· 1 shared Dingcheng Sun· 1 shared Emre Agbas· 1 shared Gwyneth WelchiD· 1 shared Haonan LiniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adele Bubnys

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1 paper

Recent·Most cited

Genome-wide CRISPR screen reveals Wnt signaling defects regulate lipid accumulation in APOE4 oligodendrocytes

Leyla Anne Akay, Anna Bright, Carles A. Boix, Kate Louderback, Janine A Medrano, Dingcheng Sun, Haonan Lin, Oisín King, Gwyneth Welch, Hiba Nawaid, Emre Agbas, Alan Y. L. Jiang, Adele Bubnys, Ji‐Xin Cheng, Joel Blanchard, Li‐Huei Tsai

The paper identifies Wnt signaling defects and GSK3b overactivity as regulators of lipid accumulation in APOE4 oligodendrocytes, showing that inhibiting GSK3b reduces lipid droplets and improves myelination.

bioRxiv · Oct 16, 2025 · PreprintNeuroscience