Author

Katharina Tepper

German Center for Neurodegenerative Diseases

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Approach:experimental assay· 1 Assay:protein structure· 1

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Christoph KlattiD· 1 shared Eckhard Mandelkow�iD· 1 shared Eva‐Maria MandelkowiD· 1 shared Jacek BiernatiD· 1 shared RamReddy Chandupatla· 1 shared Sabrina Hübschmann· 1 shared Sandra BicheriD· 1 shared Senthilvelrajan KaniyappaniD· 1 shared

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Christoph KlattORCID

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Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 16, 2020

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers

Senthilvelrajan Kaniyappan, Katharina Tepper, Jacek Biernat…·Eckhard Mandelkow�

This paper shows that FRET-based Tau seeding assays do not reflect prion-like templated assembly of Tau fibers, as GFP tags inhibit aggregation and alter fiber structure.

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protein structureexperimental assay