Coevolutionary analyses require phylogenetically deep alignments and better null models to accurately detect inter-protein contacts within and between species
Aram Avila-Herrera, Katherine Pollard
The paper evaluates coevolutionary methods for detecting inter-protein contacts within and between species, finding that deep alignments and better null models are needed for accuracy.
BMC Bioinformatics · Aug 25, 2015Peer-reviewedEvolutionary Biology