Dopaminergic neuronal dysfunction induced by newer generation systemic insecticides in Caenorhabditis elegans
Adam R. Filipowicz, Keane Bui, Nada Osman, Katherine S. Morton, Isabel W. Kenny-Ganzert, David R. Sherwood, Joel N. Meyer, Patrick Allard
This study shows that newer insecticides like flupyradifurone cause dopaminergic neurodegeneration in C. elegans, marked by dendritic blebbing and oxidative stress, which can be mitigated by antioxidants or genetic interventions.
bioRxiv · Jun 18, 2026 · PreprintNeuroscience