TSTScope Unifies Single-Cell Multi-Omics to Identify Functional T Cell States Predictive of Immunotherapy Response
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li
TSTScope integrates single-cell transcriptomics and T-cell receptor data to identify functional T cell states predictive of immunotherapy response, finding that functional state, not abundance, determines treatment outcomes.
Advanced Science · Aug 5, 2026Peer-reviewedBioinformatics