Multi-modal choroid plexus pathology in aging and Alzheimer's disease
Huixin Xu, Peter Lotfy, Benjamin Englert, Jane Oberhauser, Lillian I.J. Byer, Jasmin Wihlman, Kia Colangelo, Serhat Vahip Okar, Ashley A. Thommana, Henri A. J. Puttonen, Mikko I. Mäyränpää, Jarno Tuimala, Rute M. S. M. Pedrosa, Darshan Kumar, James Haberberger, , Maria K. Lehtinen
This study creates a multi-modal atlas of choroid plexus pathology across aging and Alzheimer's disease, identifying fibrosis, calcification, and macrophage abnormalities as key features.
bioRxiv · Jan 1, 2026 · PreprintNeuroscience