Author
Indiana University Indianapolis
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Kristen D. Onos, Olivia J. Marola, Asli Uyar…·Gareth R. Howell
This paper characterizes cerebrovascular phenotypes in WSB.APP/PS1 mice, showing age-related CAA, transcriptomic overlap with human AD, myelin deficits, and APOE allele-dependent effects on vascular pathology.
Kristen D. Onos, Peter Bor‐Chian Lin, Ravi S. Pandey…·Paul R. Territo
The paper assesses neurovascular uncoupling in APOE variants, finding APOEε4/ε4 shows Type-1 uncoupling and APOEε3/ε4 shows Type-2 uncoupling in aging mice.
Amandine Jullienne, Jenny I. Szu, Ryan Quan…·André Obenaus
This study examines vascular and metabolic changes in 5xFAD mice over time, finding sex-specific differences in vascular features and glucose metabolism linked to Alzheimer's pathology.
Alaina M. Reagan, Karen E. Christensen, Leah C. Graham…·Gareth R. Howell
This study creates a mouse model with the MTHFR 677C>T variant and shows it causes cerebrovascular deficits, supporting its use in preclinical research on vascular dementia.
Adrian L. Oblak, Kevin P. Kotredes, Ravi S. Pandey…·Gareth R. Howell
This study shows that a high fat-high sugar diet interacts with the Plcg2M28L genetic variant to accelerate Alzheimer's disease-like phenotypes in mice.