Sub-type selective muscarinic acetylcholine receptor modulation for the treatment of parkinsonian tremor
Kinsey Bickham, C Price Withers, Augusto Diedrich, Mark S. Moehle
This study tests whether selective modulation of muscarinic receptors M1, M4, or M5 can reduce parkinsonian tremor, finding no effect and suggesting M2 or M3 receptors may be responsible for anti-tremor efficacy.
bioRxiv · Apr 4, 2022 · PreprintNeuroscience