Telomere maintaining germline and somatic variants in thyroid cancer and melanoma
Sandya Liyanarachchi, Pamela L. Brock, Wei Li, Taina Tuulikki Nieminen, Nikita V. Pozdeyev, Bryan R. Haugen, Hiliary Mcrary, Bodour Salhia, Kirk Jensen, Abdul Rafeh Naqash, Varinder Kaur, Janice L. Farlow, Matthew David Ringel
The paper examines the mutual exclusivity and clinical associations of germline long-telomere syndrome variants and somatic TERT promoter mutations in thyroid cancer and melanoma, finding they are mutually exclusive but have distinct clinical impacts.
medRxiv · May 25, 2026 · PreprintGenetic & Genomic Medicine